Customization: | Available |
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CAS No.: | 98-79-3 |
Formula: | C5h7no3 |
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Introduction |
Pyroglutamic acid is 5-oxoproline. It is formed by dehydration between the α-NH2 group and the γ-hydroxyl group of glutamic acid to form an intramolecular amide bond; it can also be formed by the loss of the amido group within the glutamine molecule. If glutathione synthase is deficient, pyroglutamateemia can occur, leading to a series of clinical symptoms. Pyroglutamic acidemia is an organic acid metabolism disorder caused by glutathione Chemicalbook peptide synthetase deficiency. Clinical manifestations include onset 12 to 24 hours after birth, progressive hemolysis, jaundice, chronic metabolic acidosis, mental retardation, etc.; urine contains pyroglutamic acid, lactic acid, and α-deoxy-4-glycoacetoacetolactone. Treatment is symptomatic, and attention should be paid to adjusting diet after one year of age. |
Function |
Human skin contains a water-soluble substance with moisturizing function - natural moisturizing factor, which is roughly composed of amino acids (containing 40%), pyroglutamic acid (containing 12%), inorganic salts (Na, K, Ca, Mg, etc. (containing 18.5%), other organic matter (containing 29.5%). Therefore, pyroglutamic acid is one of the main components of the skin's natural moisturizing factor, and its moisturizing ability far exceeds that of glycerin . It is non-toxic and non-irritating and is an excellent raw material for modern skin care and hair care cosmetics. Chemicalbook Pyroglutamic acid also inhibits the activity of tyrosine oxidase, thereby preventing the deposition of "melanoid" substances in the skin and whitening the skin. It has a softening effect on cuticles and can be used in nail cosmetics. In addition to its application in cosmetics, L-pyroglutamic acid can also form derivatives with other organic compounds, which have special effects in surface activity, transparency and brightening effects. It can also be used as a surfactant for detergents; a chemical reagent for the resolution of racemic amines; and an organic intermediate. |
Application |
Used in food, medicine, cosmetics and other industries |
Curcumin | Tetrahydrocurcumin | Phycocyanin | PQQ | NMN |
NR-CL | NAD | Citicoline | Citicoline Sodium | Genistein |
Oxidized Glutathione | L-Glutathione Reduced | Alpha Lipoic Acid | R(+)-alpha-lipoic acid | DL-lipoic acid |
L-Carnosine | Beta-Glucan | Phosphatidylserine | EGCG | Theanine |
Chitosan | Chitosan oligosaccharide | Berberine hydrochloride | S-Acetyl L-Glutathione | Zeaxanthin |
Kaempferol | Urolithin A | Alpha GPC 99% 50% | Palmitoylethanolamide/PEA | Urolithin B |
Lutein | Alpha Ketoglutarate | Creatine monohydrate | Fadogia Agrestis | Boswellic acid |
Coenzyme Q10 | Astaxanthin powder/oil | Chondroitin sulfate | Magnesium threonate | Collagen |
Phenibut | BCAA | Ajuga Turkestanica Extract Turkesterone | Sulforaphane | Boric acid flakes |
Hyaluronic acid | L-carnitine | Zinc Picolinate | Ghana Seed Extract 5-HTP | Melatonin |
Resveratrol | GABA aminobutyric acid | Tauroursodeoxycholic Acid Tudca | ATP adenosine triphosphate | Artemisinin |
Oleanolic acid | Naringenin | Bovine colostrum powder | BHB-Ca/Na/Mg | Pterostilbene |
Vitamin A Series | Vitamin A Acetate Powder | Vitamin E Series | Mixed tocopherol Oil |
Vitamin A Palmitate Oil | Mixed tocopherol powder | ||
Vitamin D Series | Vitamin AD3 | D-gamma tocopherol Oil | |
Vitamin D3 Powder | D-delta tocopherol Oil | ||
Vitamin D3 Oil | D-alpha Tocopherol Oil | ||
Vitamin C (Ascorbic Acid) | Vitamin C(Ascorbic Acid) | D-alpha Tocopheryl Acetate Oil | |
Calcium Ascorbate | D-alpha Tocopheryl Acetate Powder | ||
Sodium Ascorbate | D-alpha Tocopheryl Succinate Powder | ||
Beta Carotene | Beta Carotene Powder | Vitamin K2 Series | MK-4 Powder/Oil |
Beta Carotene Oil | MK-7 Powder/Oil | ||
Vitamin B Series | B1,B2,B3,B5,B6,B7.B9.B12 | MK-9 Powder/Oil | |
Lipoic acid | Alpha lipoic acid | Vitamin K1 | Vitamin K1 |
R-(+) -lipoic acid |
L-Cysteine hydrochloride monohydrate | L-Cysteine hydrochloride anhydrous | L-Cysteine | N-Acetyl-L-Cysteine |
S-Carboxymethyl-L-Cysteine | L-Tryptophan | Glycine | L-Lysine monohydrochloride |
L-Glutamic acid | L-Threonine | L-Arginine HCI | L-Leucine |
L-Tyrosine | L-Cystine | L-Alanine | DL-Alanine |
DL-Methionine | L-Methionine | L-Arginine base | L-isoleucine |
L-Valine | L-Phenylalanine | L-Glutamine | L-Histidine |
L-Histidine monohydrochloride | L-Lysine | L-Serine | L-Citrulline |
L-Aspartic acid | L-Proline | L-Asparagine | L-Ornithine monohydrochloride |
L-Hydrotyproline | B-Alanine | Taurine | Disodium succinate |
Q: What types of cosmetic raw materials do you supply? |
We supply a wide range of cosmetic raw materials, including but not limited to whitening agents, moisturizing agents, antioxidation, emollients, surfactants, preservatives, pigments, and active ingredients to meet diverse formulation needs. |
Q: How can I place an order for cosmetic ingredients? |
To place an order, simply browse our product catalog, select the desired items, and follow the online checkout process. If you have specific requirements or need assistance, our customer service team is ready to help. |
Q: What is the minimum order quantity for your cosmetic raw materials? |
The minimum order quantity varies by product. You can find this information on the product pages or contact our sales team for specific details. Usually MOQ is from 1kg. |
Q: Can I request a sample of a specific cosmetic ingredient before placing a bulk order? |
Yes, we offer sample sizes for most of our products. You can request samples through our website, and our team will assist you in choosing the right products for your needs. |
Q: What quality standards do your cosmetic raw materials adhere to? |
Our cosmetic raw materials adhere to industry-standard quality and safety regulations. We ensure compliance with relevant standards and provide documentation, such as Certificates of Analysis, upon request. |
Q: What payment methods do you accept for cosmetic ingredient purchases? |
We accept various payment methods, including credit cards, bank transfers, and other secure online payment options. Details are available during the checkout process. |
Q: How do you ensure the timely delivery of cosmetic raw materials? |
We work with reliable shipping partners to ensure timely and secure delivery of your orders. You can track your shipment through tracking website and our customer service team is available to assist with any delivery-related inquiries. |
Q: Do you provide technical support or documentation for the proper usage of your cosmetic raw materials? |
Absolutely. We offer technical support and provide comprehensive documentation, including usage guidelines and formulation recommendations. Our team is available to address any technical inquiries you may have. |