Safe Delivery Pharmaceutical Grade API Antidepressant Antimicrobial Agents CAS 53123-88-9 Pure 99% Purity Sirolimus Rpm Rapamycin Powder

• CAS No.: 53123-88-9
• Formula: C51h79no13
• EINECS: 610-965-5
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Model NO.: Rapamycin
• Colour: White
• Product Name: Rapamycin
• Documents: COA/MSDS/TDS
• CAS No: 53123-88-9
• Application: Pharmaceutical Intermediate
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: 98%
• Trademark: Greenway
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

Introduction

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2).

Function

Rapamycin has multiple functions and can affect various biological processes in the body. Here are some of the key functions of rapamycin:

1.Immunosuppression: Rapamycin is primarily used as an immunosuppressant drug to prevent organ transplant rejection and treat certain autoimmune diseases. It suppresses the immune system by inhibiting the activation and proliferation of T-lymphocytes, a type of white blood cell involved in immune responses.

2.Inhibition of mTOR signaling: Rapamycin specifically targets a protein called mammalian target of rapamycin (mTOR) and inhibits its activity. mTOR is a central regulator of cell growth, division, and metabolism. By inhibiting mTOR, rapamycin can interfere with cell signaling pathways involved in these processes.
3.Anti-cancer effects: Rapamycin has demonstrated anti-cancer properties by inhibiting tumor growth and metastasis. By blocking mTOR signaling, it disrupts the cellular mechanisms that promote cancer cell proliferation, survival, and angiogenesis. Rapamycin and its analogs (such as everolimus and temsirolimus) have been approved for the treatment of certain cancers, including renal cell carcinoma and certain types of advanced breast cancer.
4. Anti-inflammatory properties: Rapamycin has shown anti-inflammatory effects in various disease models. It can reduce inflammation by modulating immune responses and inhibiting the production of pro-inflammatory molecules.

5.Modulation of autophagy: Autophagy is a cellular process involved in the degradation and recycling of damaged or unnecessary cellular components. Rapamycin can induce autophagy by inhibiting mTOR, leading to the enhanced removal of dysfunctional cellular components and potentially promoting cellular health and longevity.
6.Anti-fibrotic effects: Rapamycin has been investigated for its potential to inhibit the development of fibrosis, a condition characterized by excessive scarring and tissue remodeling. It can interfere with the signaling pathways involved in fibrotic processes and reduce the deposition of extracellular matrix proteins.

Application

Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway..

 

Curcumin	Tetrahydrocurcumin	Phycocyanin	PQQ	NMN
NR-CL	NAD	Citicoline	Citicoline Sodium	Genistein
Oxidized Glutathione	L-Glutathione Reduced	Alpha Lipoic Acid	R(+)-alpha-lipoic acid	DL-lipoic acid
L-Carnosine	Beta-Glucan	Phosphatidylserine	EGCG	Theanine
Chitosan	Chitosan oligosaccharide	Berberine hydrochloride	S-Acetyl L-Glutathione	Zeaxanthin
Kaempferol	Urolithin A	Alpha GPC 99% 50%	Palmitoylethanolamide/PEA	Urolithin B
Lutein	Alpha Ketoglutarate	Creatine monohydrate	Fadogia Agrestis	Boswellic acid
Coenzyme Q10	Astaxanthin powder/oil	Chondroitin sulfate	Magnesium threonate	Collagen
Phenibut	BCAA	Ajuga Turkestanica Extract Turkesterone	Sulforaphane	Boric acid flakes
Hyaluronic acid	L-carnitine	Zinc Picolinate	Ghana Seed Extract 5-HTP	Melatonin
Resveratrol	GABA aminobutyric acid	Tauroursodeoxycholic Acid Tudca	ATP adenosine triphosphate	Artemisinin
Oleanolic acid	Naringenin	Bovine colostrum powder	BHB-Ca/Na/Mg	Pterostilbene
Food Additives - Sweeteners
Stevioside	Erythritol	Sucralose	Trehalose	Polydextrose
Neotame	Stachyose	Allulose(Psicose)	Aspartame	Acesulfame
D-Ribose	D-Mannitol	D-xylose	D-arabinose	L-arabinose
Isomalt	Maltitol	Lactose	Sorbitol	Xylitol
Momordicaglycosides	Crystalline Fructose	Xylo-oligosaccharide( XOS)	Fructo-oligosaccharide(FOS)	Isomaltulose(Palatinose)

Vitamin A Series	Vitamin A Acetate Powder	Vitamin E Series	Mixed tocopherol Oil
	Vitamin A Palmitate Oil		Mixed tocopherol powder
Vitamin D Series	Vitamin AD3		D-gamma tocopherol Oil
	Vitamin D3 Powder		D-delta tocopherol Oil
	Vitamin D3 Oil		D-alpha Tocopherol Oil
Vitamin C (Ascorbic Acid)	Vitamin C(Ascorbic Acid)		D-alpha Tocopheryl Acetate Oil
	Calcium Ascorbate		D-alpha Tocopheryl Acetate Powder
	Sodium Ascorbate		D-alpha Tocopheryl Succinate Powder
Beta Carotene	Beta Carotene Powder	Vitamin K2 Series	MK-4 Powder/Oil
	Beta Carotene Oil		MK-7 Powder/Oil
Vitamin B Series	B1,B2,B3,B5,B6,B7.B9.B12		MK-9 Powder/Oil
Lipoic acid	Alpha lipoic acid	Vitamin K1	Vitamin K1
	R-(+) -lipoic acid

L-Cysteine hydrochloride monohydrate	L-Cysteine hydrochloride anhydrous	L-Cysteine	N-Acetyl-L-Cysteine
S-Carboxymethyl-L-Cysteine	L-Tryptophan	Glycine	L-Lysine monohydrochloride
L-Glutamic acid	L-Threonine	L-Arginine HCI	L-Leucine
L-Tyrosine	L-Cystine	L-Alanine	DL-Alanine
DL-Methionine	L-Methionine	L-Arginine base	L-isoleucine
L-Valine	L-Phenylalanine	L-Glutamine	L-Histidine
L-Histidine monohydrochloride	L-Lysine	L-Serine	L-Citrulline
L-Aspartic acid	L-Proline	L-Asparagine	L-Ornithine monohydrochloride
L-Hydrotyproline	B-Alanine	Taurine	Disodium succinate

 

Private Label OEM Capsules with Jar

1. Customized formulas and packaging.
2. High-quality labels and materials.
3. Various capsule capacities available.
4. Stringent printing and quality control.
5. Secure packaging and shipping.

Private Label Bag with powder

1. Customized sizel options for packaging bags.
2. Unique packaging design with customized printing.
3. Customized powder formula available.
4. Strict printing and quality control measures.
5. Secure packaging and transportation.
 

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Our cosmetic raw materials adhere to industry-standard quality and safety regulations. We ensure compliance with relevant standards and provide documentation, such as Certificates of Analysis, upon request.

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