Customization: | Available |
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CAS No.: | 104987-11-3 |
Formula: | C44h69no12 |
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Introduction |
Tacrolimus is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants and the skin condition vitiligo. |
Function |
Tacrolimus works by inhibiting the activation and proliferation of T-lymphocytes, which are responsible for the body's immune response. Specifically, it binds to a protein called FK-binding protein-12 (FKBP-12), which then inhibits the activity of calcineurin, a key enzyme involved in T-cell activation. This results in reduced cytokine production and decreased immune response, ultimately preventing rejection of transplanted organs. |
Application |
Tacrolimus is approved by the FDA for use in liver, kidney, and heart transplant recipients. It may also be used off-label to treat other autoimmune diseases such as rheumatoid arthritis and psoriasis. Tacrolimus is typically administered orally, either as a capsule or a liquid solution, and is sometimes combined with other immunosuppressive drugs such as corticosteroids. In addition to its use in transplantation, Tacrolimus has been studied for its potential in treating other conditions such as atopic dermatitis, uveitis, and ulcerative colitis. It has also been investigated for its potential as an anti-cancer agent due to its ability to inhibit T-cell activation and proliferation. However, more research is needed in these areas to determine the safety and effectiveness of Tacrolimus in these indications. |
Curcumin | Tetrahydrocurcumin | Phycocyanin | PQQ | NMN |
NR-CL | NAD | Citicoline | Citicoline Sodium | Genistein |
Oxidized Glutathione | L-Glutathione Reduced | Alpha Lipoic Acid | R(+)-alpha-lipoic acid | DL-lipoic acid |
L-Carnosine | Beta-Glucan | Phosphatidylserine | EGCG | Theanine |
Chitosan | Chitosan oligosaccharide | Berberine hydrochloride | S-Acetyl L-Glutathione | Zeaxanthin |
Kaempferol | Urolithin A | Alpha GPC 99% 50% | Palmitoylethanolamide/PEA | Urolithin B |
Lutein | Alpha Ketoglutarate | Creatine monohydrate | Fadogia Agrestis | Boswellic acid |
Coenzyme Q10 | Astaxanthin powder/oil | Chondroitin sulfate | Magnesium threonate | Collagen |
Phenibut | BCAA | Ajuga Turkestanica Extract Turkesterone | Sulforaphane | Boric acid flakes |
Hyaluronic acid | L-carnitine | Zinc Picolinate | Ghana Seed Extract 5-HTP | Melatonin |
Resveratrol | GABA aminobutyric acid | Tauroursodeoxycholic Acid Tudca | ATP adenosine triphosphate | Artemisinin |
Oleanolic acid | Naringenin | Bovine colostrum powder | BHB-Ca/Na/Mg | Pterostilbene |
Food Additives - Sweeteners | ||||
Stevioside | Erythritol | Sucralose | Trehalose | Polydextrose |
Neotame | Stachyose | Allulose(Psicose) | Aspartame | Acesulfame |
D-Ribose | D-Mannitol | D-xylose | D-arabinose | L-arabinose |
Isomalt | Maltitol | Lactose | Sorbitol | Xylitol |
Momordicaglycosides | Crystalline Fructose | Xylo-oligosaccharide( XOS) | Fructo-oligosaccharide(FOS) | Isomaltulose(Palatinose) |
Vitamin A Series | Vitamin A Acetate Powder | Vitamin E Series | Mixed tocopherol Oil |
Vitamin A Palmitate Oil | Mixed tocopherol powder | ||
Vitamin D Series | Vitamin AD3 | D-gamma tocopherol Oil | |
Vitamin D3 Powder | D-delta tocopherol Oil | ||
Vitamin D3 Oil | D-alpha Tocopherol Oil | ||
Vitamin C (Ascorbic Acid) | Vitamin C(Ascorbic Acid) | D-alpha Tocopheryl Acetate Oil | |
Calcium Ascorbate | D-alpha Tocopheryl Acetate Powder | ||
Sodium Ascorbate | D-alpha Tocopheryl Succinate Powder | ||
Beta Carotene | Beta Carotene Powder | Vitamin K2 Series | MK-4 Powder/Oil |
Beta Carotene Oil | MK-7 Powder/Oil | ||
Vitamin B Series | B1,B2,B3,B5,B6,B7.B9.B12 | MK-9 Powder/Oil | |
Lipoic acid | Alpha lipoic acid | Vitamin K1 | Vitamin K1 |
R-(+) -lipoic acid |
L-Cysteine hydrochloride monohydrate | L-Cysteine hydrochloride anhydrous | L-Cysteine | N-Acetyl-L-Cysteine |
S-Carboxymethyl-L-Cysteine | L-Tryptophan | Glycine | L-Lysine monohydrochloride |
L-Glutamic acid | L-Threonine | L-Arginine HCI | L-Leucine |
L-Tyrosine | L-Cystine | L-Alanine | DL-Alanine |
DL-Methionine | L-Methionine | L-Arginine base | L-isoleucine |
L-Valine | L-Phenylalanine | L-Glutamine | L-Histidine |
L-Histidine monohydrochloride | L-Lysine | L-Serine | L-Citrulline |
L-Aspartic acid | L-Proline | L-Asparagine | L-Ornithine monohydrochloride |
L-Hydrotyproline | B-Alanine | Taurine | Disodium succinate |
Q: What types of cosmetic raw materials do you supply? |
We supply a wide range of cosmetic raw materials, including but not limited to whitening agents, moisturizing agents, antioxidation, emollients, surfactants, preservatives, pigments, and active ingredients to meet diverse formulation needs. |
Q: How can I place an order for cosmetic ingredients? |
To place an order, simply browse our product catalog, select the desired items, and follow the online checkout process. If you have specific requirements or need assistance, our customer service team is ready to help. |
Q: What is the minimum order quantity for your cosmetic raw materials? |
The minimum order quantity varies by product. You can find this information on the product pages or contact our sales team for specific details. Usually MOQ is from 1kg. |
Q: Can I request a sample of a specific cosmetic ingredient before placing a bulk order? |
Yes, we offer sample sizes for most of our products. You can request samples through our website, and our team will assist you in choosing the right products for your needs. |
Q: What quality standards do your cosmetic raw materials adhere to? |
Our cosmetic raw materials adhere to industry-standard quality and safety regulations. We ensure compliance with relevant standards and provide documentation, such as Certificates of Analysis, upon request. |
Q: What payment methods do you accept for cosmetic ingredient purchases? |
We accept various payment methods, including credit cards, bank transfers, and other secure online payment options. Details are available during the checkout process. |
Q: How do you ensure the timely delivery of cosmetic raw materials? |
We work with reliable shipping partners to ensure timely and secure delivery of your orders. You can track your shipment through tracking website and our customer service team is available to assist with any delivery-related inquiries. |
Q: Do you provide technical support or documentation for the proper usage of your cosmetic raw materials? |
Absolutely. We offer technical support and provide comprehensive documentation, including usage guidelines and formulation recommendations. Our team is available to address any technical inquiries you may have. |