| Customization: | Available |
|---|---|
| CAS No.: | 10010-67-0 |
| Formula: | C8h19n2nao6s2 |
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Introduction |
| 1,4-Piperazinediethanesulfonic acid, abbreviated as PIPES, also known as 1-4-Piperazinediethylsulfonic acid in Chinese, is one of the sulfonic acid series buffer reagents developed by Good et al. in 1960's. It has some important characteristics shared by Good's buffer solutions, including: 1) low UV( λ≥ 260nm absorbance; 2) The water solubility is the strongest, while the solubility is the lowest among other solvents; 3) PChemicalbookKa is located in the neutral range and is not easily affected by temperature; 4) Stable pH value; 5) Low interference reaction, enzyme or chemical stability; 6) Easy to synthesize. The effective buffering range of PIPES is pH 6.1-7.5, with pKa=6.8 (25 ºC). Due to its pKa being close to physiological pH, it is suitable for cell culture. In addition, PIPES can also serve as a buffer reagent in animal and plant chemistry to minimize lipid damage and experimental artifacts caused by glutaraldehyde fixation. |
| Function |
PH buffering: PIPES monosodium salt is a pH buffering agent that can be mixed with PIPES disodium salt. By changing the ratio and total amount of monosodium and disodium salts, the pH value and ionic strength of the medium can be adjusted. Biological experiment: In cell experiments, the solubility of PIPES monosodium salt in water (H2O) is 100 mg/mL (308.31 mM; ultrasound assisted dissolution), which makes it suitable for preparing stock solutions. Storage conditions: PIPES monosodium salt should be sealed and stored at 4 ° C, away from moisture. In solvent, it can be stored for 6 months at -80 ° C and 1 month at -20 ° C (sealed and kept away from moisture). |
| Application |
Cell culture: Due to its pKa value close to physiological pH, Pipes Monomedium Salt is suitable for cell culture and helps maintain the optimal pH environment required for cell growth and physiological conditions. Organizational fixation: Used in tissue fixation under electron microscopy, Pipes Monosum Salt can minimize lipid damage and experimental artifacts caused by glutaraldehyde fixation. Biochemical research: As a non-toxic buffering agent, it is used as a buffering substance in biological, biochemical, and environmental research, and does not interact with metal ions. Fluorescence microscope: used for preparing BRB80 buffer for imaging dynamic microtubules and individual kinesin molecules through fluorescence microscopy. Universal buffer: PIPES sodium salt can be mixed with PIPES free acid or disodium salt. By adjusting the ratio and total amount of monosodium and disodium salts, the pH value and ionic strength of the medium can be adjusted. |
| VC-IP/Ascorbyl Tetraisopalmitate | Tranexamic Acid | 1,4-Dipropionyloxybenzene |
| Alpha Arbutin | Ectoin | Glycyrrhetinic Acid (18-Beta Glycyrrhetinic Acid) |
| Beta Arbutin | Dimethylmethoxy Chromanol | Dimethymethoxyl Chromanyl Palmitate |
| Deoxyarbutin | Alpha Lipoic Acid | Magnesium Ascorbyl Phosphate |
| Kojic Acid | Charcoal Powder(Bamboo) | Sodium Ascorbyl Phosphate |
| Kojic Acid Dipalmitate | Stearyl Glycyrrhetinate | Hydrocotyle Asiatica Extract |
| Ergothioneine | Tetrahydrocurcumin | Potassium 4-Methoxysalicylate |
| Carnosine | Glycolic Acid | Salicylic Acid |
| Undecylenoyl Phenylalanine | Bromelain | Alpha Hydroxy Acid/AHA |
| Caffeic acid | Mequinol | Phytic acid |
| Niacinamide | SymWhite Powder | Snow White |
| Papain | 3-o-ethyl ascorbic acid/VCE | Giga White |
| Monobenzone | Mandelic acid | Glabridin |
| Azelaic Acid | Melatonin | Dipotassium Glycyrrhizinate |
| Ascorbyl Glucoside/AA2G | L-Glutathione Reduced | Procysteine |
| Fullerence C60 | Cetyl Tranexamate HCl/TXC | Hydroxypinacolone reinoate(HPR) |
| Sodium Hyaluronate/Hyaluronic Acid | Beta-Glucan | Sodium Polyglutamate | Inositol |
| Pro-xylane/Hydroxypropyl tetrahydropyrantriol | Collagen | 2-O-β-D-glucosyl-glycerol | Glucosylglycerol |
| Biosaccharide Gum-1 | Ceramide | Orotic Acid Monohydrate | 1,2-Hexanediol |
| Sodium L-pyroglutamate;PCA-Na | D-panthenol | Maltobionic Acid | Lactobionic acid |
| Caprylyl Glycol/1,2-Dihydroxyoctane | DL-panthenol | Allantoin | Polyglutamic Acid |
| Ascorbic Acid (Vitamin C) | Magnesium Ascorbyl Phosphate | Ascorbyl Isostearate | Ascorbyl Glucoside |
| 3-o-Ethyl Ascorbic Acid | Sodium Ascorbyl Phosphate | Ascorbyl Tetraisopalmitate | Ascorbyl Palmitate |
| Apple Polyphenols | Sodium Copper Chlorophyllin | D-Isoascorbic Acid | Ferulic Acid | EGF/Oligopeptide-1 |
| Ascorbyl Palmitate | Resveratrol | Vitamin E | Copper PCA | Vitamin E |
| EUK 134 | Glucosylrutin | Pterostilbene | ZINC PCA | Coenzyme Q10 |
| Vanillyl butyl ether | Menthol Crystal | Menthyl lactate | Menthone 1,2-glycerol ketal |
| Capsaicin | WS-23 | Camphor | WS-3 |
| Q: What types of cosmetic raw materials do you supply? |
| We supply a wide range of cosmetic raw materials, including but not limited to whitening agents, moisturizing agents, antioxidation, emollients, surfactants, preservatives, pigments, and active ingredients to meet diverse formulation needs. |
| Q: How can I place an order for cosmetic ingredients? |
| To place an order, simply browse our product catalog, select the desired items, and follow the online checkout process. If you have specific requirements or need assistance, our customer service team is ready to help. |
| Q: What is the minimum order quantity for your cosmetic raw materials? |
| The minimum order quantity varies by product. You can find this information on the product pages or contact our sales team for specific details. Usually MOQ is from 1kg. |
| Q: Can I request a sample of a specific cosmetic ingredient before placing a bulk order? |
| Yes, we offer sample sizes for most of our products. You can request samples through our website, and our team will assist you in choosing the right products for your needs. |
| Q: What quality standards do your cosmetic raw materials adhere to? |
| Our cosmetic raw materials adhere to industry-standard quality and safety regulations. We ensure compliance with relevant standards and provide documentation, such as Certificates of Analysis, upon request. |
| Q: What payment methods do you accept for cosmetic ingredient purchases? |
| We accept various payment methods, including credit cards, bank transfers, and other secure online payment options. Details are available during the checkout process. |
| Q: How do you ensure the timely delivery of cosmetic raw materials? |
| We work with reliable shipping partners to ensure timely and secure delivery of your orders. You can track your shipment through tracking website and our customer service team is available to assist with any delivery-related inquiries. |
| Q: Do you provide technical support or documentation for the proper usage of your cosmetic raw materials? |
| Absolutely. We offer technical support and provide comprehensive documentation, including usage guidelines and formulation recommendations. Our team is available to address any technical inquiries you may have. |
){kind=link}