Customization: | Available |
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CAS No.: | 147-24-0 |
Formula: | C17h22clno |
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Introduction |
Diphenhydramine hydrochloride is an antihistamine drug having the chemical name 2-(Diphenylmethoxy)- N,N-dimethylethylamine hydrochloride. It occurs as a white, crystalline powder, is freely soluble in water and alcohol . |
Function |
1. Anti-allergic effect: Diphenhydramine Hydrochloride is an H1 receptor antagonist that can block the effects of histamine, thereby reducing allergic reactions and symptoms. It can relieve symptoms such as nasal congestion, sneezing, and runny nose caused by allergic rhinitis, hay fever, and food allergies.
2. Sedative and hypnotic effects: Diphenhydramine Hydrochloride has sedative and hypnotic effects and can relieve symptoms of anxiety, tension, insomnia and other symptoms through the inhibitory effect of the central nervous system. Therefore, it is also used as an over-the-counter sleep aid.
3. Anti-vomiting effect: Diphenhydramine Hydrochloride has an anti-vomiting effect. It can inhibit the reaction of the vomiting center and reduce nausea and vomiting by affecting the chemical transmitters of the central nervous system.
4. Treatment of motion sickness: Diphenhydramine Hydrochloride can be used to prevent and treat nausea and vomiting caused by motion sickness (sea sickness, motion sickness, etc.).
5. Anti-allergic dermatitis effect: Diphenhydramine Hydrochloride can be used to relieve mild allergic skin inflammation, such as contact dermatitis, urticaria, etc.
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Application |
1, skin and mucosa of allergy, such as urticaria, angioneurotic edema, allergic rhinitis, skin itch, pruritus, genital pruritus, or itching jaundice of drug eruption, insect bites and contact dermatitis are also valid. 2, acute allergic reaction, reduces allergic reactions caused by blood transfusion or plasma; often applied before the transfusion antihistamine such as diphenhydramine, usually given to diphenhydramine hydrochloride 40 mg intramuscularly, and pay attention to the screening of blood donors, try not to use with a history of allergy blood donors. To avoid repeating the same blood donors of blood infusion to prevent Antigen-antibody reaction occurs, such as the blood present in the body when there is anti-IgA antibodies, infusion of red blood cells after washing, this method of washing clears donor blood, the IgA in order to prevent the occurrence of allergic reactions. 3, motion sickness-sickness prevention, has strong antiemetic effect can also be used for prevention and treatment of radiation sickness, vomiting after surgery, drug-induced nausea and vomiting; 4, for Parkinson's disease and extrapyramidal symptoms; 5, sedative, hypnotic and preoperative dose; 6, dental anesthesia, when patients allergic to common local anesthetics high 1% diphenhydramine hydrochloride liquid can be used as a local anesthetic for dental; 7, antitussive, as a non-addictive cough medicine is suitable for treating a cold or cough caused by allergies, but its antitussive effects have not been sure. |
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